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Gait dynamics in mouse models of Parkinson's disease and Huntington's disease

Ivo Amende1†, Ajit Kale2†, Scott McCue2, Scott Glazier2, James P Morgan1 and Thomas G Hampton1,2*

1 Division of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215 USA

2 The CuraVita Corporation, Boston, MA 02109 USA

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Journal of NeuroEngineering and Rehabilitation 2005, 2:20 doi:10.1186/1743-0003-2-20

Published: 25 July 2005

Additional files

Additional File 1:

Movie of the ventral view of a C57BL/6J saline-treated mouse walking at a speed of 34 cm/s. File is playable using Windows Media Player.

Format: AVI Size: 2.7MB Download file

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Open Data

Additional File 2:

Movie of the ventral view of a 3NP-treated (cumulative dose 75 mg/kg) C57BL/6J mouse attempting to walk at a speed of 34 cm/s, demonstrating coordinated gait of the forelimbs but gait failure of the hind limbs. Compare this to the coordinated gait of the forelimbs and hind limbs in a saline-treated C57BL/6J mouse (1). Files areplayable using Windows Media Player.

Format: AVI Size: 3.2MB Download file

Playing the movie within this page requires QuickTime 3 or later and JavaScript. Read more

Open Data